Frederick Unverzagt, Ph.D.

Frederick W. Unverzagt, Ph.D.
Professor of Clinical Psychology in Clinical Psychiatry
Professor of Clinical Medical and Molecular Genetics


Personal Statement 

My research focuses on cognition in age-related diseases particularly Alzheimer disease.  One strong theme in my research is the epidemiology of Alzheimer disease.  I also investigate the heterogeneity of Mild Cognitive Impairment and conduct randomized clinical trials of the effectiveness of non-pharmacologic interventions to improve cognition and delay onset of dementia.  In addition to research, I actively promote the professional practice of psychology and have been elected to the boards of the Indiana Psychological Association, the American Board of Clinical Neuropsychology (the primary board certification organization in neuropsychology), and the Association of Postdoctoral Programs in Clinical Neuropsychology (a membership organization of residency training programs).



Undergraduate: Southern Illinois University at Carbondale

Graduate School: Southern Illinois University at Carbondale

Internship: Milwaukee County Medical Center

Fellowship: Medical College of Wisconsin

Board Certifications/Certifications:

American Board of Professional Psychology-Clinical Neuropsychology

Current Academic Interests 

Teaching: I am the Residency Training Director for the Clinical Neuropsychology Residency, an APPCN-affiliated, two-year residency in Clinical Neuropsychology.   I also provide lectures on neuropsychological assessment, functional neuroanatomy, neurobiology of memory, dementia, and Alzheimer disease to psychology graduate students and medical students, interns, and residents.

Clinical: I founded the Neuropsychology Clinic in Psychiatry at Indiana University School of Medicine and provide assessment and diagnosis of the full spectrum of neurobehavioral pathologies including:  Alzheimer disease, Lewy Body disease, fronto-temporal disease, stroke, multiple sclerosis, brain tumor, traumatic brain injury, and occupational exposure.   I also perform independent medical examinations for insurance companies and attorneys.

Research My research interests are focused on the clinical assessment of memory loss and cognitive impairment associated with neurodegenerative disease and breast cancer. I developed a brief, reliable, and valid telephone-based cognitive assessment battery for use in breast cancer research, the Indiana University Telephone-based Assessment of Neuropsychological Status (IU-TBANS). I have also developed and adapted cognitive assessments for use in cross-cultural studies in Nigeria, Kenya, Jamaica, and China. I am site PI for one of the largest randomized, controlled trials of a cognitive intervention ever undertaken, the ACTIVE (Advanced Cognitive Training for Independent Vital Elderly) study.

Recent Publications

Tsivgoulis G, Psaltopoulou T, Wadley VG, Alexandrov AV, Howard G, Unverzagt FW, Moy C, Howard VJ, Kissela B, & Judd SE. (2015).  Adherence to a Mediterranean diet and prediction of incident stroke.  Stroke, 46 (3), 780-785.  DOI: 0.1161/STROKEAHA.114.007894

Kim S, Nho K, Ramanan VK, Lai D, Foroud TM, Lane K, Murrell JR, Gao S, Hall KS, Unverzagt FW, Baiyewu O, Ogunniyi A, Gureje O, Kling MA, Doraiswamy PM, Kaddurah-Daouk R, Hendrie HC, & Saykin, AJ. (2015).  Genetic influences on plasma homocysteine levels in African Americans and Yoruba Nigerians. Journal of Alzheimer's Disease, 49 (4), 991-1003.  DOI:10.3233/JAD-150651

Gao S, Ogunniyi A, Hall KS, Baiyewu, O, Unverzagt FW, Lane KA, Murrell JR, Gureje O, Hake AM, & Hendrie HC. (2016).  Dementia incidence declined in African Americans but not in Yoruba. Alzheimer’s & Dementia, 12 (3), 244-251.  DOI: 10.1016/j.jalz.2015.06.1894

Kim S, Nho K, Ramanan VK, Lai DB, Foroud TM, Lane K, Murrell JR, Gao SJ, Hall KS, Unverzagt FW,  Baiyewu O, Ogunniyi A, Gureje O, Kling MA, Doraiswamy PM, Kaddurah-Daouk R, Hendrie HC, & Saykin AJ. (2016).  Genetic influences on plasma homocysteine levels in African Americans and Yoruba Nigerians. Journal of Alzheimer’s Disease, 49 (4), 991-1003, DOI: 10.3233/JAD-150651

Levine DA, Galecki AT, Langa KM, Unverzagt FW, Kabeto MU, Giordani B, & Wadley VG. (2016). Trajectory of cognitive decline after incident stroke. Journal of the American Medical Association, 314 (1), 41-51.  DOI: 10.1001/jama.2015.6968


Frederick Unverzagt, Ph.D.

Goodman Hall
355 W. 16th Street
Suite 2800
Indianapolis, IN 46202
(317) 963-7301

Department of Psychiatry | 355 W. 16th St., Suite 4800 | Indianapolis, IN 46202 | Ph: (317) 963-7288 | Fax: (317) 963-7313